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The Los Angeles Dodgers and Arizona Diamondbacks meet tonight at Dodger Stadium to decide their three-game set. The Dodgers are the betting favorite to win and clinch the mini-series. Check out our latest MLB betting picks below to see who we’re backing to take the win.
- What: MLB
- Who: LA Dodgers vs. Arizona Diamondbacks
- Where: Dodger Stadium, Los Angeles, CA.
- When: Wednesday, May 21st, 2025
- Time: 8.10 p.m. ET
The Los Angeles Dodgers ended their four-game losing streak with a dramatic 4–3 extra-inning win over the Arizona Diamondbacks at Dodger Stadium on Tuesday.
The Dodgers carried a 1–0 lead into the ninth inning before Gabriel Moreno tied the game for Arizona with a solo home run off reliever Tanner Scott.
In the 10th, Corbin Carroll put the Diamondbacks ahead 3–1 with a two-run homer.
But the Dodgers responded quickly. Tommy Edman hit an RBI double to cut the deficit, and Will Smith was hit by a pitch with the bases loaded to even the score at 3–3.
TOMMY EDMAN OPPOSITE FIELD RBI DOUBLE pic.twitter.com/qrVr0o43zI
— Jack (@MidWestLAFan) May 21, 2025
Max Muncy then sealed the comeback with a walk-off sacrifice fly to end the losing skid.
The series is now tied at 1-1. But unlike in their shared four-match series in Arizona earlier this month, there is only one match remaining, so someone will leave with the series win tonight.
LA Dodgers vs. Arizona Diamondbacks Betting
After losing a fourth consecutive match in their 9-5 series opener defeat to the Diamondbacks, the Dodgers started Game 2 of the series as the -230 betting favorites, with the Diamondbacks at +190.
After Tuesday night’s close run 4-3 win, the Dodgers have been cut to just -135 to win Game 3 on the money line. LA is +145 to win on the run line and cover the 1.5-run spread.
As for the Diamondbacks, they are +115 to win on the money line and -175 to win with the +1.5-run advantage on the handicap spread line.
The total run line is set at 9. Over and under is both -110.
Find more wagering options on our betting table below. All our odds for the match between the LA Dodgers and the Arizona Diamondbacks are taken from the best MLB baseball betting sites in 2025.
For more information on baseball betting, you can check out our World Series Betting Guide page.
| Dodgers vs. Diamondbacks |  |  |  |
| Dodgers | -135 | -135 | -135 |
| Diamondbacks | +115 | +115 | +115 |
| Dodgers (-1.5) | +145 | +145 | +145 |
| Diamondbacks (+1.5) | -175 | -175 | -175 |
| Over 9 | -110 | -110 | -110 |
| Under 9 | -110 | -110 | -110 |
LA Dodgers
The Dodgers are 4-6 in their ten outings. Despite their poor run of form, they still lead the NL West with a 30-19 record.
Ahead of the currently tied series with the Diamondbacks, the expensively assembled franchise faced a challenging three-game series against their cross-town rivals, the Los Angeles Angels.
Despite strong individual performances, including Shohei Ohtani’s 16th home run of the season, the Dodgers were swept by the Angels, losing all three games.
Manager Dave Roberts expressed disappointment in the team’s performance, highlighting deficiencies in the Dodgers’ roster compared to the Angels.
Despite the recent setbacks, the Dodgers are still the +225 betting favorites to win the 2025 World Series.
Dave Roberts’ team is also the -600 betting favorites to win the NL West and the +140 favorite to win the National League.
Arizona Diamondbacks
The Arizona Diamondbacks are 6-4 across their last ten outings. They sit fourth in the NL West with a 26-23 record. They are four games back on the Dodgers.
Ahead of facing Dave Roberts’ LA team, Arizona opened their recent three-game series against the Colorado Rockies with a commanding 8-0 Shutout victory.
The series continued with a high-scoring affair in Game 2, where the Rockies rallied from a five-run deficit to win 14-12, despite strong offensive efforts from the Diamondbacks.
However, Arizona bounced back in the series finale, securing a 1-0 victory behind Ketel Marte’s first-inning home run and Merrill Kelly’s dominant pitching performance, where he struck out 11 over seven scoreless innings.
Arizona is +1500 to win the NL West. They are +1800 to win the National League and +3300 to be crowned World Series champions.
LA Dodgers vs. Arizona Diamondbacks Betting Picks and Prediction
The Dodgers went into Game 2 at -230 on the money line. After a close 4-3 win, they will start the third and deciding match at just -135.
That’s a significant price swing and is representative of just how much the Dodgers have struggled in recent days.
Nevertheless, Tuesday night’s comeback victory could serve as a momentum shift for Los Angeles.
With their offense showing signs of life and a potential rebound in pitching performance, the Dodgers look good to take the match and the series.
Tuesday night’s win wasn’t spectacular. And it wasn’t achieved in the usual flamboyant style we have come to expect from LA. It was a win that was ground out with pure grit and determination.
This is what champions do. They win the dirty games, and we feel that sets LA up to win the series. They are an attractive -135 on the money line, which is a good price and a worthy pick.
We’re going for the bigger payout and backing the Dodgers to cover the -1.5 run line at +145.
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