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- What? MLB: New York Yankees vs. San Francisco Giants
- When? Wednesday, March 25, 2026
- Where? Oracle Park in San Francisco, CA
The San Francisco Giants, who went 81–81 last season, will host the New York Yankees, who finished 94–68, at Oracle Park on Wednesday. New York is a slight -115 favorite, while San Francisco is priced at +105. The total is set at 7 runs, with Max Fried and Logan Webb expected to start.
Below are the MLB betting lines from three of the best MLB Baseball betting sites.
| MLB |  |  |  |
| New York Yankees | -115 | -115 | -115 |
| San Francisco Giants | +104 | +105 | +104 |
| New York Yankees -1.5 | +153 | +155 | +153 |
| San Francisco Giants +1.5 | -175 | -175 | -175 |
| Over 7 | -105 | -105 | -105 |
| Under 7 | -115 | -115 | -115 |
New York Yankees
New York posted a .455 slugging percentage last season, striking out 1,463 times while drawing 639 walks. The lineup produced 820 RBIs and 1,371 hits, finishing with a .251 team batting average. As a group, the Yankees recorded 255 doubles and launched 274 home runs, totaling 849 runs scored with a .332 on-base percentage. Their 5.2 runs per game ranked first in the league.
On the pitching side, the staff registered a 2.59 strikeout-to-walk ratio and a 1.25 WHIP. Yankees arms allowed 175 home runs and 685 total runs, ranking 15th in MLB, while giving up 1,239 hits (7.7 per nine innings) and 625 earned runs. The team posted a 3.91 ERA, good for 14th in the league, and struck out 1,440 batters against 557 walks, finishing with a collective 4.00 FIP.
The bullpen was frequently called upon, entering with runners on base 167 times and appearing in 165 high-leverage situations. Relievers recorded 100 holds, ranking ninth in the league, and converted 43 saves with a 67.2% success rate, failing in 21 of 64 opportunities. Of the 255 inherited runners, 27.5% came around to score, while the Yankees used 533 relievers over the course of the season.
Defensively, New York totaled 4,319 putouts along with 1,389 assists and 94 errors, finishing with a .986 fielding percentage that ranked 13th in the majors, while turning 105 double plays. They converted 70.8% of balls in play into outs across 12,957 innings, placing sixth in baseball.
Max Fried owns a 92-41 career record with a 2.99 FIP, having faced 4,415 major league hitters. He has allowed 947 hits at a rate of 7.9 per nine innings and issued 297 walks. Fried carries a 3.04 ERA with 364 earned runs allowed and a 1.153 WHIP, totaling 1,079 innings pitched and 1,052 strikeouts in his career.
San Francisco Giants
San Francisco totaled 173 home runs last season while driving in 672 runs. They also recorded 239 doubles, drew 556 walks, and scored 705 runs overall. The Giants posted a .311 on-base percentage alongside a .235 team batting average. Their .386 slugging percentage contributed to an average of 4.35 runs per game, ranking 17th in MLB. As a lineup, they struck out 1,380 times, placing 12th in the league, and collected 1,261 hits.
San Francisco’s pitching staff finished last season with a 1.298 WHIP and a 3.74 FIP, posting a strikeout-to-walk ratio of 8.50 with 1,358 strikeouts against 506 walks. The Giants ranked 21st in MLB in hits allowed with 1,354, while surrendering 143 home runs and 4.30 runs per nine innings, placing 15th in the league. In total, the staff gave up 684 runs, including 612 earned, resulting in a 3.84 ERA.
In 152 save situations, the Giants recorded 89 holds and 22 blown saves. Their bullpen converted 41 of 63 save opportunities and appeared in 173 high-leverage spots, along with 122 outings featuring inherited runners. Relievers allowed 36.8% of inherited runners to score, and the unit posted a 65.1% save rate, ranking 10th in MLB, while deploying 515 pitchers out of the bullpen over the season.
Defensively, San Francisco posted a 68.4% efficiency rate across 12,903 innings, ranking 26th in the majors. The Giants turned 134 double plays and logged a .984 fielding percentage, which placed 23rd in baseball. The team also recorded 1,523 assists, 95 errors, and 4,301 putouts.
Logan Webb has allowed 1,020 hits and recorded 994 strikeouts over 1,062 innings in his career. He has given up 399 earned runs while posting a 1.196 WHIP and a 3.30 FIP. With a 3.98 strikeout-to-walk ratio, Webb has faced 4,350 batters and owns a 70-53 record, along with a 3.38 ERA and an average of 8.6 hits allowed per nine innings.
New York Yankees vs. San Francisco Giants Betting Pick
New York enters this matchup with clear advantages on both sides of the ball, led by an elite offense that topped the league in scoring and consistently generates power and on-base production. With Max Fried on the mound, the Yankees also hold the edge in starting pitching. His consistency and ability to limit baserunners should neutralize San Francisco’s lineup. When factoring in New York’s overall balance, superior run production, and slight edge on the mound, the Yankees are in a strong position to come away with the win.
Below are the best offshore sportsbooks where you can place your New York Yankees vs. San Francisco Giants bets.
Moneyline betting 