AL Wild Card: Yankees vs. Red Sox Betting Odds & Picks

  • Date & Location: Tuesday, October 5, 2021 at Fenway Park, Boston, MA
  • Odds: Yankees (-117) vs. Red Sox (+107) via BetOnline
  • Prediction: Yankees to win 5-4

The New York Yankees (92-70, 46-35 Away) face the Boston Red Sox (91-70, 49-32 Home) in the 2021 American League Wild Card game. Fenway Park in Boston hosts the game on Tuesday, October 5. The Yankees enter the winner-take-all game having won their past six games against the Red Sox. The victor moves on to face the Tampa Bay Rays in the AL Division Series.

Please check to our MLB 2021 betting guide for baseball betting tips and advice with the World Series closing in.


The Red Sox might do well to pitch around Aaron Judge and Giancarlo Stanton. Both Yankees have hit 10 home runs since the start of September. Stanton has done well against Boston all season. He has four home runs and 14 RBIs on 17 hits. Gleyber Torres also has four home runs and 17 hits against the Sox. The shortstop earned 13 RBI’s.

Boston only had one standout offensive player against New York in 2021. That player was Rafael Devers. The third baseman had 17 hits, five home runs and 18 RBIs against the Yankees.

Youtube video thumbnail



The Yankees will start Gerrit Cole on the mound, while the Red Sox will put their trust in Nathan Eovaldi.

Cole finished 2021 with a record of 16-8, 3.23 ERA, and 243 strikeouts. Cole struggled in September. He went 3-2 and posted a 5.16 ERA in six starts. Cole went 2-2 against Boston this year with a 4.91 ERA.

Eovaldi has an 11-9 record in 2021 with a 3.75 ERA, and 195 strikeouts. Eovaldi has an ERA of 3.71 in six starts against New York in 2021.

Cole gives New York the edge in pitching. He is 10-4 on the road and he is a big game pitcher.

Prediction: Yankees to beat Red Sox at -118 via BetUS

New York Yankees To Beat Boston Red Sox
Bet now



Boston finished 2021 poorly. After the Yankees swept them, they lost two of three to Baltimore. New York went 6-3 against three 90-win teams to wrap up the regular season.


Both teams had 92-70 records this year. The Red Sox won 10 games of the 19 games these teams played in 2021. What stands out about the matchup is that the Yankees won the last six games the two teams played against each other That includes a sweep at Fenway in September.

The Yankees are just the better team at this time and they will beat the Red Sox to move on to face Tampa Bay.

Pick: Yankees to defeat Red Sox at -117 via SportsBetting

New York YankeesTo Beat Boston Red Sox
Bet now

See below a list of reliable sportsbooks and choose the best one for you.




50% up to $1,000

Bet Now




100% up to $1,000

Bet Now




125% Sports Bonus - up to $2,500

Bet Now
Trent Reinsmith

Trent covers UFC and MMA for MTS. He has written for USA Today Sports, Vice, Bloody Elbow, Fight! Magazine, UFC 360, and Narratively among others. He has been involved with MMA since he and some friends threw some money together to purchase the pay-per-view of UFC 1, and the rest is history.

Learn how to find the best betting sites Here!