Japanese MotoGP picks: Marquez seeks seventh world title with win at Motegi

  • What: Japanese Grand Prix
  • Date: Friday, September 26-28, 2025
  • Location: Mobility Resort Motegi
  • Where: Motegi, Japan

MotoGP’s 2025 Japanese round at Mobility Resort Motegi, set for September 26-28, is a season-defining event.

Marc Marquez holds a commanding 182-point lead over his younger brother Alex—the only other rider with a mathematical chance at the title—making this a pivotal championship weekend.

This is Marc Marquez’s first shot at securing the World Championship, and the stakes soar at Honda’s home race. Honda will make a bold statement, sending Takaaki Nakagami roaring back as a wildcard with the Honda HRC Test Team for his fourth MotoGP appearance this year.

Momentum is building for the Japanese manufacturers, with both Yamaha and Honda surging forward in 2025 after recent struggles.

Honda created Motegi in 1997 as a world-class test ground, featuring a 2.9-mile international-standard road course in the picturesque northern Kanto district.

As the first flyaway race following the European rounds, the Motul Grand Prix of Japan presents a new challenge and potential turning point for the season.

The Japanese Grand Prix is known for its dramatic battles, and with the championship on the line, this weekend could deliver another unforgettable MotoGP moment. Honda’s home advantage, the resurgence of Japanese manufacturers, and the stakes for Marquez make this a must-watch event.

Before we look at the betting breakdown and picks for the 2025 Japanese GP, check out the best sites for MotoGP betting and our betting picks for the 2025 MotoGP Championship.

2025 Japanese MotoGP Odds

To Win 2025 Japanese Moto GPBetOnline Sportsbook & Casino Review 2026BetUS Sportsbook Review 2026Bovada Sportsbook Review 2026
Marc Marquez-250-225-225
Alex Marquez+400+400+400
Francesco Bagnaia+900+900+900
Marco Bezzecchi+1100+1100+1100
Enea Bastianini+1800+1800+1800
Fabio Quartararo+1800+1800+1800
Pedro Acosta+2200+2200+2200
Fabio Di Giannantonio+2800+2800+2800
Franco Morbidelli+4000+4000+4000
Brad Binder+5000+5000+5000
Fermin Aldeguer+6000+6000+6000
Johann Zarco+8000+8000+8000
Jorge Martin+8000+8000+8000
Raul Fernandez+8000+8000+8000
Joan Mir+8000+8000+8000
Maverick Vinales+8000+8000+8000
Luca Marini+15000+15000+15000
Jack Miller+20000+20000+20000
Ai Ogura+25000+25000+25000
Alex Rins+25000+25000+25000
Miguel Oliveira+25000+25000+25000
Lorenzo Savadori+100000+100000+100000

Marc Marquez

Marc Marquez enters Motegi as the overwhelming favorite. The odds are heavily stacked in his favor to seal his ninth world title at the MotoGP Grand Prix of Japan at Mobility Resort Motegi. Perhaps the only obstacle is whether he can control his nerves after five seasons without a championship.

With such a commanding points lead and multiple scenarios for clinching the title, Marquez remains the clear favorite. His experience and proven ability under pressure stand out. Marquez’s return to championship-winning form aboard the Ducati has been remarkable. Motegi could provide the perfect stage for his coronation.

Marc MarquezTO WIN 2025 Japanese MotoGP
★★★★★
-250
Bet now

Alex Marquez

Alex Marquez faces an almost impossible task. He is the only rider mathematically capable of preventing his brother from celebrating his title.

Despite being 182 points behind with limited rounds remaining, the younger Marquez has shown resilience throughout the season. He won’t surrender easily. His familiarity with the Motegi circuit and determination to delay Marc’s championship could make him a spoiler.

The mathematics are overwhelmingly against him. Still, Alex’s presence adds a touch of family drama to the weekend. He’ll be motivated to perform at his highest level on Honda’s home turf, potentially setting up emotional scenes regardless of the championship outcome.

Alex MarquezTO WIN 2025 Japanese MotoGP
★★★★★
+400
Bet now

Francesco Bagnaia

Francesco Bagnaia heads to Motegi determined to turn his season around after enduring ten races without a podium finish.

The two-time world champion has admitted to “throwing away” his 2025 campaign. However, encouraging signs emerged as he topped Friday’s opening practice session at Motegi.

Ducati plans to implement solutions from its Misano test in the hope of helping Bagnaia regain his competitiveness. He is reportedly running a 2024-spec fork and swingarm on his GP25 as he searches for answers.

Bagnaia needs to recapture his championship form to finish the year strong and rebuild his confidence heading into 2026.

Francesco BagnaiaTO WIN 2025 Japanese MotoGP
★★★★★
+900
Bet now

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Tony Reyes

Tony is a pro sports journalist who dedicates most of his free time to watching the latest matches and games on TV. When he's not participating in sports-related activities or seeing his friends, Tony enjoys outdoor activities such as hiking, cycling, and basketball. In addition to being a sports expert, Tony has extensive knowledge of finances and accou...

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