Updated 2021 NCAA Tournament Odds Heading Into Sweet 16

  • BetOnline, Bovada and BetUS have updated odds for the 16 teams still remaining in the 2021 NCAA March Madness tournament 
  • The Final Four is set to begin on April 3, with the title game being played April 5 at Lucas Oil Stadium
  • Gonzaga (+150), Baylor (+325) and Michigan (+850) are the three No. 1 seeds still in contention  

After a bracket-busting opening weekend of the NCAA men’s basketball tournament saw four double-digit seeds secure their spots in the Sweet 16, let’s look at the updated national championship odds now that No. 1 Illinois, No. 2 Ohio State, No. 3 West Virginia and No. 4 Virginia have all been knocked out.

And make sure to refer to our Ultimate March Madness Betting Strategy Guide if you need any tips or advice.

2021 College Basketball National Championship Odds

Loyola Chicago+1200+1600+1400
Florida State+1600+2000+1700
Oregon State+4000+6500+6000
Oral Roberts+6600+10000+7500

Gonzaga still the favorite

Sister Jean and No. 8 Loyola-Chicago eliminated No. 1 Illinois from the tournament on Saturday, but three No. 1 seeds are still alive in kicking in the Sweet 16: Gonzaga (+150), Baylor (+325) and Michigan (+850).

Now just four victories shy of the first undefeated season since Indiana in 1976, the Bulldogs face No. 5 Creighton (+2800) on Sunday while the Bears match up with No. 5 Villanova (+3300) on Saturday. The last two times the Wildcats reached the Sweet 16, in 2016 and 2018, they went on to win the national championship, but Baylor is a 6.5-point favorite after winning six of their past seven games.

The top-seeded Wolverines advanced to their fourth-straight Sweet 16 after narrowly surviving No. 8 LSU on Monday and will tip off with No. 4 Florida State (+1600) on Sunday.  The winner of that contest gets the winner of the regional semifinal between No. 2 Alabama (+1200) and No. 11 UCLA (+4000).
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Cinderella Stories

After shocking No. 2 Ohio State and No. 7 Florida in the opening weekend, Oral Roberts (+6600) can become the first No. 15 seed in history to advance to the Elite Eight if they defeat No. 3 Arkansas (+1800) on Saturday.

Meanwhile, No. 8 Loyola Chicago (+1200) is in the Sweet 16 for the second time in the last three tournaments following their beatdown of Illinois. The Ramblers face No. 12 Oregon State (+4000), who pulled off two upsets of their own in beating No. 5 Tennessee and No. 4 Oklahoma State.

Jim Boeheim is in his 20th Sweet 16 in 45 seasons after No. 11 Syracuse (+4000) used stifling defense to take down No. 6 San Diego State and No. 3 West Virginia in the opening rounds. The Orange play No. 2 Houston (+900) on Saturday.

When making futures bets this weekend, be sure to shop around as all the sportsbooks have wildly different numbers. For instance, BetOnline offers great value on Alabama at +1200, Florida State (+2000) and Creighton (+5500) are nice buys on Bovada, and BetUS is the place to shop if you like Arkansas (+1200).

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Steve Starr

Steve is one of the many Americans who spends Sunday watching football on the couch and gorging on heart-clogging eats. He describes himself as a good father, great dog owner, and mediocre gambler and husband.

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