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Week 8 of the college football season promises plenty of excitement, with the odds board featuring multiple top-20 clashes. The SEC takes center stage this week, highlighted by Tennessee visiting Alabama as 8-point underdogs, LSU facing off against Vanderbilt with a 2.5-point edge, and Georgia going up against Ole Miss at -7.5.
Elsewhere, notable spreads include BYU as 3-point underdogs at Utah and Notre Dame favored by 9.5 points against USC, setting up some intriguing matchups across the country.
- What? 2025 College Football Week 8
- Where? USA
- When? Friday, October 17 – Saturday, October 18, 2025
Tennessee vs. Alabama
Below are the odds from three of the best college football betting sites.
| NCAAF |  |  |  |
| Tennessee | +252 | +252 | +255 |
| Alabama | -310 | -310 | -310 |
| Tennessee +8 | -106 | -106 | -105 |
| Alabama -8 | -114 | -114 | -115 |
| Over 58.5 | -110 | -110 | -110 |
| Under 58.5 | -110 | -110 | -110 |
The marquee game of the week features No. 11 Tennessee traveling to Tuscaloosa to take on No. 6 Alabama. Both squads narrowly escaped tough SEC contests last Saturday, each winning by just three points. The Volunteers (5-1 straight up, 3-3 against the spread, 2-1 in conference) edged Arkansas 34-31, while the Crimson Tide (5-1 SU, 4-2 ATS, 3-0 SEC) managed a 27-24 victory over Missouri. Alabama quarterback Ty Simpson continues to make a strong case for the Heisman, tossing for 200 yards and three touchdowns. The Tide has steadily elevated its play each week and enters this matchup performing more efficiently on both offense and defense.
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LSU vs. Vanderbilt
LSU has dominated this series, winning the last 10 matchups, including a 24-17 victory in Baton Rouge last year. The Tigers’ offense under Garrett Nussmeier has been inconsistent, producing four touchdowns but also four interceptions in three SEC contests. Vanderbilt will need to prove it can generate points against one of the nation’s top-five scoring defenses, while quarterback Diego Pavia must avoid costly red-zone mistakes. As a road underdog under Brian Kelly, LSU enters this game with a 2-3 record both straight up and against the spread.
Georgia vs. Ole Miss
Ole Miss looks to maintain its unbeaten start and strengthen its playoff résumé with another strong performance, while Georgia is determined to end the Rebels’ streak and notch its fourth SEC win of the season. With both programs targeting the postseason, the outcome of this game could carry major implications for their playoff positioning. This showdown is shaping up to be a high-stakes clash that college football fans won’t want to miss.
BYU vs. Utah
BYU enters this week’s ‘Holy War’ having taken the last two matchups, making the spread somewhat surprising. The Cougars remain undefeated, but Utah’s quarterback Devon Dampier poses a dual threat with a 71.5% completion rate and an average of 5.8 yards per carry. On the other side, BYU’s Bear Bachmeier has thrown for seven touchdowns with just one interception. Ultimately, this game may come down to which signal-caller can deliver in the fourth quarter.
Notre Dame vs. USC
This historic rivalry sees both programs aiming to make an impact this week. Notre Dame, after a slow start to the season, has hit its stride and enters this game riding a four-game winning streak. The Fighting Irish are likely to assert themselves on their home turf, but USC’s talent and depth—ranked inside the top 25—make them capable of keeping the game within the spread.
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