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- What? College Football 2025 Season Week 4
- Where? USA
- When? Saturday, September 20, 2025
The 2025 college football campaign is heating up as conference matchups start to dominate the schedule.
In the Big XII, Texas Tech squares off with Utah, while the SEC slate features Auburn battling Oklahoma. Over in the Big Ten, Illinois heads to Bloomington to challenge Indiana.
Both Utah and Texas Tech rose four places in this week’s AP rankings, setting the stage for the winner to climb even higher—potentially making a statement with a decisive performance.
Meanwhile, Miami continues its stretch of in-state showdowns, facing Florida this week. A victory there, paired with a stumble from Ohio State, Penn State, or LSU, could open the door for the Hurricanes to break into the top three.
Texas Tech Raiders vs. Utah Utes
Below are the odds for this college football week 4 clash from three of the best college football betting sites.
| NCAAF |  |  |  |
| Texas Tech | +146 | +149 | +149 |
| Utah | -170 | -170 | -170 |
| Texas Tech +3.0 | -105 | -103 | -103 |
| Utah -3.0 | -115 | -117 | -117 |
| Over 58 | -105 | -105 | -105 |
| Under 58 | -115 | -115 | -115 |
Sports betting sites give Utah the edge in this contest, setting their moneyline at -170, while Texas Tech sits as the +149 underdog. The spread is a tight three points, leaning toward the Utes to take care of business.
The Red Raiders have leaned heavily on their explosive offense to start the season. They’ve already posted eye-popping totals, dropping 67 on Arkansas-Pine Bluff and 62 against Kent State. Their passing attack has been especially dangerous, highlighted by a 466-yard aerial performance versus Oregon State.
Utah, on the other hand, comes into this matchup with a more balanced identity. They gashed Wyoming for 311 rushing yards while also showing efficiency through the air, putting up 245 passing yards against Cal Poly. Defensively, the Utes have been no less impressive—twice holding opponents under double digits.
Laying the three points with Utah looks like the smarter angle here. While Texas Tech has covered well on the road in recent seasons, this marks their first trip away from home in 2025, adding an element of uncertainty. Salt Lake City has been a fortress for the Utes, who have won 24 of their last 29 at Rice-Eccles Stadium. Their defense is also among the best in the country, currently ranked 11th in points allowed.
Texas Tech has thrived in games with high totals, going 5-0 in such situations, but facing a disciplined and physical Utah defense on the road is a very different challenge compared to their early-season opponents.
In the end, the Utes’ combination of home-field advantage, defensive consistency, and offensive balance makes them the more trustworthy side. Look for Utah to separate in the second half and cover the short spread in a hard-fought but convincing win.
Auburn vs. Oklahoma
Oklahoma’s defense has been the story of their college football season so far. Shutting down Temple and Illinois State wasn’t unexpected, but holding No. 21 Michigan to just 13 points in Week 2 showed how tough this unit can be against real competition.
Quarterbacks have struggled mightily against the Sooners—Bryce Underwood never found a rhythm through the air, and opposing starters are connecting on fewer than 46% of their throws this year. That spells trouble for Auburn, a team already lacking offensive balance. With Jackson Arnold averaging under 170 passing yards per game, it’s hard to envision the Tigers consistently moving the ball.
Trends also favor a low-scoring battle. Oklahoma has cashed the under in five of its last seven games at home, and the combination of their suffocating pass defense with Auburn’s offensive limitations points in that same direction. Expect the Sooners to keep control in Norman and continue leaning on their defensive dominance.
Illinois Fighting Illini vs. Indiana Hoosiers
Both defenses have been sharp early in the season, with Illinois allowing only 22 points and Indiana giving up 23. That kind of consistency suggests this matchup could lean toward a slower-paced, lower-scoring affair. Additionally, while Indiana’s offense has been productive, Illinois’ defense has shown the ability to shut down opponents. Ranking 8th nationally in points allowed, the Illini are well-equipped to limit explosive plays. The last time these two teams squared off, the total stayed under 47.5, reinforcing the case for another defensive battle. Neither side looks positioned to consistently break through against the other’s front seven. All signs point to a grind-it-out game where both defenses dictate the flow. The under 52.5 is the smart play, with points likely coming at a premium.
Florida vs. Miami
Florida has a strong track record of high-scoring games after a defeat, hitting the over in 13 of their last 19 such situations. That bounce-back pattern points to an offense that tends to respond aggressively, and with the Gators sitting 49th nationally in points scored, they should be capable of holding up their end of the total.
Miami, meanwhile, has been even more dangerous with the ball. The Hurricanes have already piled up 121 points, ranking 19th in the country, and their sharp passing attack is built to test Florida’s secondary throughout four quarters.
Both defenses have put up respectable early numbers—Miami has allowed 39 points (25th nationally) and Florida 38 (24th nationally). Still, when faced with more dynamic offenses, both units could be stretched beyond those averages.
This sets up as a contest where the offenses take center stage. With enough playmakers on both sidelines to sustain scoring drives, the over 50.5 looks like the most appealing angle. Expect both teams to trade blows in a matchup that should climb past the posted total.
Below is our partner table of the best offshore sportsbooks where you can place your college football week 4 bets.
Sports Betting Sites 