2021 CFL Grey Cup Picks: Hamilton Tiger-Cats Open As Favorites

  • Bovada favors the Hamilton Tiger-Cats to win the 2021 Grey Cup
  • The Canadian Football League’s 14-game season begins on Aug. 5 with the 108th Grey Cup being held in Hamilton on Dec. 12
  • Winnipeg (+450) is the defending champion but Calgary (+450) has 12 consecutive seasons with double-digit wins

It has been a long wait for fans of the Canadian Football League after COVID-19 forced the cancellation of the entire 2020 season. With talks of a potential CFL-XFL partnership having come to an end, the nine Canadian teams across the league will open training camp on Saturday in preparation for a shortened 14-game season.

Before the CFL season kicks off on Aug. 5, let’s take a look at the opening odds to win the 108th Grey Cup in Hamilton on Dec. 12.

Remember that betting on the CFL is like betting on the NFL or any other football competition. Learn how to bet on football right here.

Odds to win 2021 Grey Cup

Hamilton Tiger-Cats+275
Saskatchewan Roughriders+400
Calgary Stampeders+450
Winnipeg Blue Bombers+450
Montreal Alouettes+500
Toronto Argonauts+750
BC Lions+800
Edmonton Elks+1000
Ottawa Redblacks+1000

Hamilton Tiger-Cats open as favorites

The Tiger-Cats opened as +275 favorites to win the 108th Grey Cup on their home field. Back in 2019, Hamilton recorded its first 15-win season in franchise history, scoring the most points and allowing fewest of any team in the CFL. They then cruised through the postseason before getting pummeled 33-12 by Winnipeg in the Grey Cup.

The Ti-Cats will return from a 20-month layoff with most of their roster in-tact and the league’s strongest quarterback duo with Dane Evans and Jeremiah Masoli, who suffered a season-ending injury in 2019.

The Saskatchewan Roughriders (+400) are next on the board despite losing four players to Achilles injuries during a workout session last week. Yikes. Luckily, 29-year-old quarterback Cody Fajardo, the West Division’s Most Outstanding Player in 2019, and CFL all-star Shaq Evans were not among the injured players.

Hamilton Tiger-CatsTo Win 2021 Grey Cup
Bet now
Saskatchewan RoughridersTo Win 2021 Grey Cup
Bet now

Bombers set to defend their title

In 2019, Winnipeg (+450) never surrendered more than 14 points in consecutive playoff wins over Calgary, Saskatchewan, and Hamilton (three of the four highest-scoring teams in the league) to snap the CFL’s longest championship drought with a Grey Cup victory.

That fearsome Blue-Bombers defense should also get a boost from Canadian defensive lineman Jonathan Kongbo after he couldn’t find a home in the NFL. With fourth consecutive seasons of double-digit wins, Winnipeg has a chance to go back-to-back.

The best value on the board, however, is the Stampeders (+450), who have reeled off a dozen straight seasons of double-digit wins that include seven first-place finishes, six Grey Cup appearances, and three championships.

Heading into a year of unknowns following a canceled season, Calgary is easily the safest bet on the board.

Calgary StampedersTo Win 2021 Grey Cup
Bet now

See below the top sportsbooks where you can wager online and choose the best one for you:




50% up to $1,000

Bet Now




100% up to $1,000

Bet Now




125% Sports Bonus - up to $2,500

Bet Now

Steve Starr

Steve is one of the many Americans who spends Sunday watching football on the couch and gorging on delicious eats. He describes himself as a good father, great dog owner, and mediocre gambler and husband.

Learn how to find the best betting sites Here!