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The Los Angeles Chargers will visit the Jacksonville Jaguars at EverBank Stadium in Week 11 of the 2025 NFL season. The Chargers are entering this game with a 7-3 record, having won their last three games, including a 25-10 win over the Pittsburgh Steelers. The Jaguars, with a 5-4 record, are looking to bounce back after a 36-29 loss to the Houston Texans. Stay with us for our Jaguars vs Chargers prediction and expert pick.
- National Football League
- Jacksonville Jaguars vs Los Angeles Chargers
- Sunday, November 16, 2025 1:00 PM
- 1:00 PM
- EverBank Stadium, Jacksonville, FL
- CBS
Best NFL Bets: Jaguars vs Chargers Betting Odds
The betting odds for the Los Angeles Chargers versus the Jacksonville Jaguars have seen movement. The line opened with the Chargers favored by 3 points, and it remains steady at -3.0 with odds of -106. The Jaguars are +3.0 with odds of -113. On the moneyline, the Chargers are favored at -154, while the Jaguars stand at +129. The total points for the game are set at 43.5, with the over at -114 and the under at -107. These odds reflect the Chargers’ strong road record and the Jaguars’ competitiveness at home.
| NFL |  |  |  |
| Tampa Bay Buccaneers | +207 | +203 | +205 |
| Detroit Lions | -250 | -240 | -245 |
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Chargers Take on Jaguars: Previewing the Los Angeles Chargers
The Los Angeles Chargers will visit the Jacksonville Jaguars. This game is set for November 16, 2025, at EverBank Stadium. The Chargers are favored by 3 points with a total of 43.5.
The Chargers have been strong in recent games. They won their last three games, including a 25-10 win over the Pittsburgh Steelers. Their offense scored a total of 402 points last season, ranking 11th in the league.
Quarterback Justin Herbert leads the Chargers. He has thrown for 2,610 yards and 19 touchdowns this season. Herbert’s performance ranks him second in passing yards in the league.
The Chargers’ defense is also performing well. They are ranked first in the league, allowing only 301 points against them. They have recorded 46 sacks, placing them fifth in the league.
Injuries could impact the Chargers. Key players like Najee Harris and Rashawn Slater are out for the season. Others, like Oronde Gadsden and Keandre Lambert-Smith, are listed as questionable.
Jaguars Ready for Challenge at EverBank Stadium
The Jacksonville Jaguars are set to play against the Los Angeles Chargers at EverBank Stadium. The Jaguars have had a challenging season, ranking low in offensive stats. They are ranked 24th in passing yards with 3477 and 25th in rushing yards with 1729.
On defense, the Jaguars have struggled, allowing 435 points, which ranks them 25th. They have recorded 34 sacks, ranking 15th, and have shown some success in forcing turnovers with 6 interceptions and 3 fumbles recovered. However, they have given up a total of 6629 opponent yards, placing them at 31st in the league.
The Jaguars recently faced the Houston Texans and lost 36-29. They managed 19 first downs and recorded 119 passing yards, while rushing for 94 yards. Despite the loss, some players like Travis Etienne Jr. and Trevor Lawrence had solid performances.
Jacksonville has faced some injuries, with key players like Eric Murray and Travis Hunter out for the season. Brian Thomas Jr. and others are questionable, impacting their depth. This could influence their performance against the Chargers.
In betting trends, the Jaguars are 3.0-point underdogs with a total set at 43.5 for this game. They have shown resilience at home, winning four of their last six games at EverBank Stadium. The Jaguars will aim to capitalize on their home advantage to improve their standing.
Best NFL Bets: Expert Jaguars vs Chargers Prediction
The Los Angeles Chargers are favored by 3 points against the Jacksonville Jaguars. The Chargers have a strong season record of 7-3, with a road record of 3-1. This shows they can perform well away from home.
The Chargers’ defense ranks first in opponent score from last season, indicating they can limit the Jaguars’ offensive output. Meanwhile, the Jaguars rank 24th in offensive score from last season, which may struggle against the Chargers’ defensive strength.
Playing at EverBank Stadium, the Jaguars have a home record of 3-2 this season. However, their recent performance against top teams does not inspire confidence. The Chargers have also won their last three games, showing momentum.
The projected final score is Chargers 27, Jaguars 20. This supports the pick of Chargers -3 at odds of -106. With their strong defense and recent form, the Chargers are likely to cover the spread.
Odds are accurate at time of writing but subject to change.
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