Steve Starr
- BetOnline has NFL Week 18 lines, spreads and over/unders for every Saturday and Sunday game
- The Chargers are 2.5-point road favorites over the Chargers in a winner-take-all finale to the 2021 season
- San Francisco (+4) needs a win against the NFC West rival Rams to secure a berth in the postseason
Exercise caution before placing any wagers on the first-ever Week 18 of the NFL season. With some teams having already clinched a playoff spot and others eliminated from postseason play altogether, determining who’s motivated to win this weekend can be tricky.
We’ll examine the full slate of games and offer some smart bets to capitalize on. Also, be sure to check out the best betting sites for NFL football in 2021 and get advice on how to bet on the NFL playoffs.
NFL Week 18 – Saturday and Sunday games
 | Spread | Money Line | Total Points |
| Kansas City Chiefs | -10 (-106) | -435 | Ov 43.5 (-110) |
| Denver Broncos | +10 (-114) | 355 | Un 43.5 (-110) |
| Dallas Cowboys | -7½ (-101) | -300 | Ov 42.5 (-110) |
| Philadelphia Eagles | +7½ (-119) | 250 | Un 42.5 (-110) |
| Green Bay Packers | -2 (-110) | Ov 42 (-110) | |
| Detroit Lions | +2 (-110) | Un 42 (-110) | |
| Chicago Bears | +2½ (-110) | 120 | Ov 44.5 (-110) |
| Minnesota Vikings | -2½ (-110) | -140 | Un 44.5 (-110) |
| Indianapolis Colts | -16 (-105) | -1050 | Ov 44.5 (-110) |
| Jacksonville Jaguars | +16 (-115) | 675 | Un 44.5 (-110) |
| Tennessee Titans | -10 (-112) | -525 | Ov 42.5 (-110) |
| Houston Texans | +10 (-108) | 420 | Un 42.5 (-110) |
| Washington Football Team | -6½ (-113) | -290 | Ov 38.5 (-105) |
| New York Giants | +6½ (-107) | 245 | Un 38.5 (-115) |
| Pittsburgh Steelers | +3½ (-110) | 169 | Ov 41.5 (-115) |
| Baltimore Ravens | -3½ (-110) | -194 | Un 41.5 (-105) |
| Cincinnati Bengals | -1 (-115) | Ov 42 (-115) | |
| Cleveland Browns | +1 (-105) | Un 42 (-105) | |
| New England Patriots | -7 (-110) | -310 | Ov 40 (-110) |
| Miami Dolphins | +7 (-110) | 260 | Un 40 (-110) |
| New York Jets | +16½ (-110) | 635 | Ov 43.5 (-110) |
| Buffalo Bills | -16½ (-110) | -870 | Un 43.5 (-110) |
| Carolina Panthers | +8 (-110) | Ov 42.5 (-110) | |
| Tampa Bay Buccaneers | -8 (-110) | Un 42.5 (-110) | |
| New Orleans Saints | -4½ (-108) | -210 | Ov 40 (-108) |
| Atlanta Falcons | +4½ (-112) | 180 | Un 40 (-112) |
| Seattle Seahawks | +6½ (-105) | 230 | Ov 48 (-110) |
| Arizona Cardinals | -6½ (-115) | -275 | Un 48 (-110) |
| San Francisco 49ers | +4 | 185 | Ov 42.5 (-110) |
| Los Angeles Rams | -4 | -215 | Un 42.5 (-110) |
| Los Angeles Chargers | -2½ | -140 | Ov 42.5 (-110) |
| Las Vegas Raiders | +2½ | 120 | Un 42.5 (-110) |
Raiders (+2.5) over Chargers
The 2021 season concludes with a “winner-take-all” game between the Chargers and Raiders on Sunday Night Football, unless this unlikely scenario unfolds. Left for dead after suffering a 48-9 loss to the Chiefs in Week 14, Las Vegas has rallied to a 9-7 record with three straight victories over the Browns, Broncos and Colts. With star tight end Darren Waller set to return to the lineup, we expect the resilient Raiders to win a tight game over a Chargers franchise with a rich history of coming up small in big moments.
Next week's Chargers-Raiders game is expected to be a win or go home matchup, and @SteveKornacki explains why.
📺: NBC and @peacockTV pic.twitter.com/8oRXrlImbf
— Sunday Night Football on NBC (@SNFonNBC) January 3, 2022
Jaguars (+16) over Colts
Everyone will have an eye on this one. Why? If the Colts win, they’re in. But if the NFL’s worst franchise was to score an upset victory at home, that would open the playoff door for the winner of the Ravens vs. Steelers game (assuming the Chargers and Raiders don’t work together to secure a tie on Sunday night). Somehow, some way, Indianapolis hasn’t won in Jacksonville since 2014. While that streak should end this weekend, the 2-14 Jaguars will be plenty motivated to keep things closer than their AFC South rivals would like.
49ers (+4) over Rams
San Francisco clinches a postseason berth with a win over Los Angeles or a Saints loss to the Falcons. However, Sean McVay’s club will also be plenty motivated because they need a win to clinch the NFC West title and a first-round home game in the playoffs. Given the 49ers have won five in a row in this series, including a 31-10 victory back in November, and are facing a more dire “do or die” scenario, we like Kyle Shanahan to empty out the cupboard of Trey Lance plays to secure a W and a playoff spot.
The #49ers can clinch a playoff spot next week with a win against The Rams or a Saints loss against The Falcons ❤️💛 pic.twitter.com/I76SapyXnu
— OurSF49ers (@OurSf49ers_) January 3, 2022
Rest Scenarios To Capitalize On
With the Green Bay Packers having already clinched the NFC’s No. 1 seed, the Detroit Lions (+2) are a strong bet to pick up their third win of the season. Cincinnati will also have nothing to play for if the Chiefs defeat the Broncos on Saturday, so we expect Joe Burrow and the Bengals star receiver duo to rest against a Browns club trying to finish strong with Case Keenum under center. Take Cleveland (+2.5) while you can.
It’s also fair to wonder how motivated the Buccaneers will be to secure the NFC’s No. 2 seed given they’d also need a Rams loss to earn it. Expect Tampa Bay to pull its starters after the first half, giving the Panthers an excellent shot to cover the 8 points.
See below the top sportsbooks where you can wager online and choose the best one for you:
