Updated 2021 Australian Open Odds Heading Into Quarter-Finals

  • BetOnline and Bovada have updated odds on the Men’s and Women’s 2021 Australian Open heading into the quarter-finals
  • Novak Djokovic (+165) remains the favorite in the men’s singles draw despite suffering an abdominal injury
  • 2019 champion Naomi Osaka (+150) is chalk on the woman’s side, but Serena Williams (+450) is still alive and kicking 

If Novak Djokovic goes on to capture his ninth Australian Open title and his 18th Grand Slam title, it will likely go down as the most impressive performance of his magnificent career.

After gutting out an abdominal tear to win his third-round match in five sets, the 33-year-old Serbian advanced to the quarter-finals with a 7-6 4-6 6-1 6-4 victory over 14-seed Milos Raonic, becoming only the second man (after Roger Federer) to record 300 match wins at the four Grand Slam championships. 

Who else is still alive in the first major of the tennis season? Let’s check out the latest tournament odds for both the Men’s and Women’s draws.

Men’s Australian Open 2021 Odds

More tennis betting resources can be found here.

Djokovic dealing with an injury down under

Looking to pull ever closer to Federer and Rafael Nadal’s record of 20 Grand Slam singles titles, Novak Djokovic (+165) is still favored to win in Melbourne despite playing with an injury that could “cause more damage” to his body. “If it’s any other tournament than a Grand Slam, I would retire, withdraw from the event, that’s for sure,” said Djokovic after his fourth-round win.

The World No. 1 is set to face Alexander Zverev (+700) in the quarter-finals – our pre-tournament best bet at +1600. The sixth-seeded German is only 2-5 all-time against the Joker, with his last head-to-head victory coming in 2018, but if Djokovic’s injury proves too much to overcome, Zverev will receive a soft semi-final draw against the winner of Russian qualifier Aslan Karatsev (+6600) and No. 18 seed Grigor Dimitrov (+1400), who landed a shocking straight-set victory over No. 3 seed Dominic Thiem in the round of 16.

Rafael Nadal (+450) hasn’t won an Australian Open since 2009, but the door to a record-breaking 21st Grand Slam title could be wide open if Djokovic’s injury knocks him out of the tournament. The 34-year-old Spaniard has a dreamy quarter-finals draw against No. 6 seed Stefanos Tsitsipas (+800), who he has beat in six of seven career matchups.

Fourth-seed Daniil Medvedev (+300) is 3-0 all-time against countryman, and likely quarter-final opponent, Andrey Rublev (+1200). Assuming he advances to the semi-finals, one has to wonder if the 24-year-old Russian has the mental fortitude to outlast Nadal. Amidst blowing a two-set lead in a third-round match he eventually won, the temperamental Medvedev yelled at his coach Gilles Cervara so much that he eventually packed up and left.

The Pick: Rafael Nadal (+500 at BetOnline)

Rafael Nadalto win Australian Open
+500
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Alexander Zverevto win Australian Open
+700
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Women’s Australian Open 2021 Odds

Serena Williams looks for 24th Grand Slam title

After recovering from double match point down to defeat No. 14 seed Garbiñe Muguruza in the round of 16, three-time grand slam champion Naomi Osaka (+150) should cruise in the quarter-finals against unseeded 35-year-old Hsie Su-wei of Taiwan.

Of much more interest is the quarters clash between Osaka’s idol Serena Williams (+450) and No. 2 seed Simona Halep (+600), a two-time major winner who beat French Open champion Iga Swiatek 3-6, 6-1, 6-4 in the fourth round. Looking for an eighth Australian Open title and record-tying 24th Grand Slam championship, the 39-year-old Williams enjoys a 9-2 head-to-head record over Halep, but the 29-year-old Romanian thrashed Williams in their last meeting, the 2019 Wimbledon final.

Playing her first competitive tennis in a year, World No.1 Ashleigh Barty (+250) has yet to drop a set heading into her quarter-finals matchup with No. 25 seed Karolina Muchova (+2000). Given the lesser competition on her side of the draw, the Australian native is a good bet to be playing in the finals against whoever survives and advances out of Osaka, Williams, and Halep.

The Pick: Naomi Osaka (+150 at BetOnline)

Serena Williamsto win Australian Open
+450
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Steve Dominey

Steve has almost 15 years of experience in marketing, PR and sports television. After acquiring a Journalism degree from Carleton University, he assembled highlight packs for Canada's most-watched sports network (TSN) before transitioning to a career in communications. He describes himself as a good father, great dog owner, and mediocre gambler and husband.