NFL Week 5 Betting Preview – Bills vs 49ers

The Buffalo Bills need to bounce back after they were dismantled by the Patriots last weekend; their next opponent is another Super Bowl caliber team as they visit  the Bay Are to take on the San Francisco 49ers, this Sunday at 4:25 PM ET.

Buffalo was beating the Patriots 21-7 before they couldn’t stop a 35 point storm by New England in the second half of the game. “It’s one that will hang with us,” said Ryan Fitzpatrick, who threw four touchdowns and a season-high four interceptions. “You try to block it out with Chan’s (coach Gailey) 24-hour rule and all that, and you hope it doesn’t linger into the next game”.

“When you have two guys rushing for 100 yards, something’s up,” end Mario Williams said. “We have to have a reality check and see what’s going on”.

The 49ers had one of the outstanding performances last week as they shut down the NY Jets 34-0 at Metlife Stadium. “For sure, the whole week there was more of an edge — it was just a bad taste in your mouth,” said Alex Smith, who had season lows of 21 attempts, 12 completions and 143 yards while not throwing a TD against the Jets. “I don’t think that goes away in one day. We wanted to be 3-1 and got it done”.

“This is more the way we are accustomed to playing,” coach Jim Harbaugh said.

The road teams have won the last two games in the series between the 49ers and the Bills.

Geoff Johnson

MTS co-founder Geoff Johnson is a lifelong Mets fan, something he can't do anything about. He has a great track record when it comes to wagering on baseball – largely because he's more than willing to bet against the Mets. His career profits are impressive, but not quite as good as his handsome friend Frank Lorenzo. He wishes he hadn't let Frank write his profile.