NFL Week 8 Picks and Predictions for all of Sunday’s Games

  • BetOnline has NFL Week 8 lines, spreads and over/unders for every game on the Sunday slate
  • Derrick Henry and Jonathan Taylor will go head-to-head in the Titans-Colts AFC South division tilt
  • Jameis Winston will look to get revenge against Bruce Arians and a Buccaneers team that dumped him for Tom Brady

Entering Week 8, the early-season mystery surrounding the NFL’s 32 franchises is all but gone. We know what clubs are good, bad, potentially Super Bowl odds favorites, and borderline unwatchable.

So when making our weekly picks, we’ll ignore Sunday’s mismatches (Rams vs. Texans, Bills vs. Dolphins, etc.) and contests between non-playoff teams (Eagles vs. Lions, Jaguars vs. Seahawks, etc.) and instead focus on the division rivalry games across the league.

But before we look at all the Week 8 money lines, totals and point spreads, here’s where you can find the top betting sites for NFL football in 2021, as well as NFL MVP betting resources.

NFL Week 8 – Sunday Slate

BetOnlineSpreadMoney LineTotal Points
Miami Dolphins+13½ (-107)+640Ov 49.5 (-110)
Buffalo Bills-13½ (-113)-900Un 49.5 (-110)
Carolina Panthers+2½ (+104)+135Ov 46 (-107)
Atlanta Falcons-2½ (-124)-155Un 46 (-113)
Philadelphia Eagles-3½ (-105)-180Ov 48 (-108)
Detroit Lions+3½ (-115)+160Un 48 (-112)
Tennessee Titans-1½ (-111)-125Ov 49.5 (-115)
Indianapolis Colts+1½ (-109)+105Un 49.5 (-105)
Los Angeles Rams-14½ (-105)-1000Ov 47.5 (-110)
Houston Texans+14½ (-115)+660Un 47.5 (-110)
Cincinnati Bengals-10 (-111)-475Ov 43 (-110)
New York Jets+10 (-109)+385Un 43 (-110)
Pittsburgh Steelers+4 (-112)+170Ov 42.5 (-107)
Cleveland Browns-4 (-108)-195Un 42.5 (-113)
San Francisco 49ers-3½ (+101)-165Ov 39.5 (-110)
Chicago Bears+3½ (-121)+145Un 39.5 (-110)
Jacksonville Jaguars+3 (+105)+150Ov 43.5 (-110)
Seattle Seahawks-3 (-125)-170Un 43.5 (-110)
New England Patriots+5½ (-111)+205Ov 49 (-110)
Los Angeles Chargers-5½ (-109)-245Un 49 (-110)
Washington Football Team+3 (-115)+132Ov 43 (-110)
Denver Broncos-3 (-105)-152Un 43 (-110)
Tampa Bay Buccaneers-5 (-110)-228Ov 50 (-110)
New Orleans Saints+5 (-110)+198Un 50 (-110)
Dallas Cowboys-2½ (-110)-140Ov 54.5 (-115)
Minnesota Vikings+2½ (-110)+120Un 54.5 (-105)

Steelers (+4.0) over Browns

After losing 17 straight at Heinz Field, Cleveland dismantled the Steelers 48-37 in last year’s wild-card round. The victory was supposed to usher in a new era of winning football for the franchise, however, the Browns are just 4-3 this season and quarterback Baker Mayfield is likely to miss at least another game.

Coming off their bye week, Pittsburgh is 3-3 after beating up on bad Broncos and Seahawks teams. Ben Roethlisberger’s offense is only averaging 19.5 points per game, but that might be enough against Case Keenum if the Steelers can shutdown Nick Chubb in his return from a calf injury.

Colts (+1.5) over Titans

Who in their right mind would wager against a 5-2 Titans club coming off back-to-back statement wins against the Bills and Chiefs? Especially one that already beat the Colts  25-16 in Week 3. Still, Indianapolis is picking up steam after a slow start with three victories in four games since that loss and a near-win against Baltimore on Monday night.

While Tennesses has the NFL’s rushing leader and MVP contender Derrick Henry, Indy has the next best thing in dynamic second-year back Jonathan Taylor, who has 437 total yards and five scores in his last three games. With another solid performance from Carson Wentz, Frank Reich will split the season series with Mike Vrabel for the third-consecutive season.

Pittsburgh SteelersTo Cover vs. Browns
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+4.0
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Indianapolis ColtsTo Cover vs. Titans
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+1.5
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Buccaneers (-5.0) over Saints

New Orleans defeated Tampa Bay handily in both 2020 regular season meetings before dropping their divisional-round playoff matchup to the eventual Super Bowl champions. While the Saints are an impressive 4-2 in year one without Drew Brees, they’ll have trouble scoring points against the 6-1 Buccaneers if Sean Payton saddles Jameis Winston with the usual safe and run-heavy gameplan.

Leading the league in both passing yards (2275) and passing TDs (21) this season, Tom Brady will continue to rack up points in the Big Easy this Halloween.

Vikings (+2.5) over Cowboys

This one isn’t a division tilt, of course, but it is in front of Al and Cris on Sunday Night Football so it counts as one of Week 8’s biggest games. Both teams are coming off their bye week, yet 3-3 Minnesota should be extra motivated with a murderer’s row of opponents (Cowboys, Ravens, Chargers, Packer) upcoming over the next month.

While Dallas is averaging 10 points more per game on offense than the Vikings, who suffered a 31-28 home loss to the Cowboys just last season, Mike Zimmer’s club absolutely needs this game. Forget about Kirk Cousins’ history of struggling in primetime versus quality opponents. With Justin Jefferson, Adam Thielen and a heavy dose of Dalvin Cook, he can squeak out a victory at home.

Minnesota VikingsTo Cover vs. Cowboys
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+2.5
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Steve Starr

Steve is one of the many Americans who spends Sunday watching football on the couch and gorging on delicious eats. He describes himself as a good father, great dog owner, and mediocre gambler and husband.