Xing Cai
The qualifying rounds of the 2022 U.S. Open are done, and the real action began on Monday, August 29. Not surprisingly, we are itching to uncork our best bets to win it all. Since we already dropped our best bets to win the 2022 U.S. Open Women’s Championship, it’s on to the men’s division. And with Novak Djokovic unable to participate, we can’t help but wonder whether Rafael Nadal is poised to win the trophy for the first time since 2019.
Before we get into our top picks, here’s a look at the latest online betting options for the 2022 U.S. Open, courtesy of the folks from Bovada:
| Pick to Win |  |
| Daniil Medvedev | +230 |
| Rafael Nadal | +380 |
| Carlos Alcaraz | +500 |
| Nick Kyrgios | +1000 |
| Stefanos Tsitsipas | +1600 |
| Jannik Sinner | +1800 |
| Taylor Fritz | +2200 |
| Matteo Berrenttini | +2900 |
| Felix Auger-Aliassime | +3600 |
| Borna Coric | +4000 |
| Cameron Norrie | +4500 |
| Hubert Hurkacz | +6500 |
| Casper Ruud | +6500 |
| Andrey Rublev | +12000 |
| Pablo Carreno Busta | +6500 |
| Marin Cilic | +6500 |
| Denis Shapovalov | +10000 |
| Sebastian Korda | +12000 |
| Frances Tiafoe | +13000 |
| Dominic Thiem | +14000 |
| Jack Draper | +14000 |
| Robert Bautista Agut | +15000 |
| Andy Murray | +16000 |
| Alex de Minaur | +16000 |
| John Isner | +17000 |
| Botic van de Zandischulp | +23000 |
| Tommy Paul | +25000 |
| Karen Khachanov | +23000 |
| Miomir Kecmanovic | +23000 |
| Maxime Cressy | +23000 |
Please remember to double-check these betting odds to win the 2022 U.S. Open until you actually place your wager. The men’s championship round won’t be taking place until Monday, September 12, so these tennis betting lines are bound to move a bunch as the tournament unfolds.
If you still need a place to bet on the 2022 U.S. Open, we’ve got you covered. Our reviews of the top rated online sportsbooks are designed to help you spot the best betting sites for all sports on the market.
Without further ado, let’s get to our top picks to win the 2022 U.S. Open Men’s Championship.
Should Rafael Nadal be Favored to Win It All?
It’s easy to come up with reasons why Rafael Nadal won’t win the 2022 U.S. Open. Not only is he 36, but he’s still working his way back from an abdominal injury that prompted him to miss a handful of important tournaments. His stamina might not be up to the heat and humidity he’s going to face in Flushing, New York.
Still, that’s not quite good enough to close the door on his going for a 23rd career Grand Slam title. Nadal remains one of the best tennis players in the world, someone who is closer to his prime than not. In fact, depending on how the bracket shakes out, a U.S. Open victory could vault him into the No. 1 spot on the world rankings latter.
Though it’s fair to be concerned about how Nadal’s abdominal injury could impact his serving, he continues to boast one of the craftiest ground games in existence. His change-of-pace strokes and ability to work pinpoint angles ensures he should ensure he’s playing into mid-September once more.
Why Daniil Medvedev is Getting More Love Than Rafael Nadal
Surprised Daniil Medvedev is getting more love than Rafael Nadal? You shouldn’t be.
Medvedev is the world’s No. 1 player at this writing, and more than that, he’s also the defending U.S. Open Champion. Many have even speculated that he’s the no-brainer pick to win it all now that Novak Djokovic won’t be competing.
Controlling his first serve will be mission critical. Where someone like Rafael Nadal knows how to tone down the speed in favor of placement, Medvedev opts for power over everything. That’s entirely allowed when you’re still dropping in 60 percent of your first serves, but it can sometimes get him into trouble.
Beyond this, however, there’s not much cause for concern. Medvedev is winning 75 percent of his service games, and he’s getting better at forcing break opportunities after winning opening points.
John Isner Could be an Interesting 2022 U.S. Open Dark Horse Bet
At 37, John Isner is not someone you should consider a favorite at the 2022 U.S. Open. That honor is reserved for players like Daniil Medvedev and Rafael Nadal. At the same time, players with size and huge serves can go on incredible runs when operating on the hard courts in Flushing.
Isner falls under that umbrella. At 6’10”, he has a monster first serve, and it’s one he still converts nearly 70 percent of the time. Even more tantalizing, Isner continues to win 85 percent of his first serve points.
Indeed, this could be a very boom-or-bust proposition. Isner’s backhand has slowed down in recent years, and he cannot cover the baseline as well given his advanced age. But for those who have the iron stomach necessary to take risks, we also view Isner as more than just a stab-in-the-dark candidate.
Carlos Alcaraz Could Leave 2022 U.S. Open as World’s No. 1
Carlos Alcaraz is yet another player who has a chance to finish as the World’s No. 1 if he wins the 2022 U.S. Open. Currently sitting in the No. 4 spot, he has started to sway even the loudest critics by creating one of the tour’s best all-around packages.
Sure, there are players who hit harder and faster. But Alcaraz has become a whiz at exhausting opponents with his placement on groundstrokes—especially his knack for pushing them back deep and then dropping in shallow looks.
Plenty of people worry about how his size (6’0″) will hold up when he comes to the net. But that should really only be an issue when going up against certain opponents. Overall, Alcaraz has a claim to be one of the two or three most well-rounded players in Flushing.
2022 U.S. Open Men’s Prediction
There is a real appeal to going with Carlos Alcaraz and his 5-to-1 payout. The brand of tennis he’s been championing lately is beyond enviable.
In the end, though, we’re most drawn to Rafael Nadal.
There is some risk given his return from an abdominal injury, but it’s also been forever since he entered the U.S. Open paying out nearly 4-to-1. Given the relative lack of experience in this setting at the top of the bracket, this feels like an opportunity for him to remind the world that just because he’s older, it doesn’t mean he’s done.
MTS Prediction: Rafael Nadal (+380)
Take a look at this list of the top online sportsbooks so you can decide which one to use for all of your 2022 U.S. Open betting:
